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Pharmaceutical Guideline
Pharmacopoeia

DEIONIZED WATER

Deionized Water is produced by an ion-exchange process in which the cations & anions are replaced with H+ & OH− ions by use of ion-exchange

Pharmaceutical Guideline1 min read
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Plastic jerrycan with a blue and orange label reading Deionised Water

DEIONIZED WATER

Plastic jerrycan with a blue and orange label reading Deionised Water

  • Deionized Water can be produced by starting with either Drinking Water orPurified Water , depending upon the monograph or testing procedures defined in the compendia.
  • Deionized Water is produced by an ion-exchange process in which the cations and anions are replaced with H+ and OH− ions by use of ion-exchange resins.
  • Similar to Distilled Water, Deionized Water is used primarily as a solvent for reagent preparation, but it is also specified in the execution of other aspects of tests, such as for transferring an analyte within a test procedure, as a calibration standard or analytical blank, and for test apparatus cleaning.
  • Also, none of the cited uses of this water imply any needed purity attribute that can only be achieved by deionization.
  • Therefore, water meeting the requirements for Purified Water that is derived by other means of purification could be equally suitable where Deionized Water is specified.
  • It is the user’s responsibility to verify the suitability of Purified Water .
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